Glycomet (Metformin)

Strength(s): 500 mg

Active Ingredient: Metformin



Glycomet is a medication that’s usually prescribed as a first-line medication towards the treatment of type-2 diabetes, meaning that it is among the first options prescribed once a patient has been diagnosed with the condition. Patients are able to buy Glycomet cheaply from online pharmacies in Canada. It’s taken orally in pill form and has proven to be particularly effective in people who are obese or overweight. It hasn’t been associated with weight gain in patients who use it.

This drug is also prescribed to patients suffering from a condition known as polycystic ovary syndrome. There is some evidence to suggest that it plays a role in the prevention of the cancerous complications brought about as a result of diabetes as well as certain cardiovascular conditions and diseases.

How it works

Our body requires a certain amount of glucose for its day-to-day energy requirements, but when certain systems fail, the levels of glucose in our body will rise to harmful levels. Glycomet belongs to a class of anti-diabetic drugs known as biguanides which work by delaying the absorption of glucose from the gastrointestinal tract into the bloodstream. It also increases the body’s insulin sensitivity and thereby brings about a reduction in the liver’s glucose production. These two actions go towards maintaining glucose levels in the bloodstream within tolerable bounds.

Side effects and contraindications

Whenever you are considering any medication, it’s always best to know as much as possible about how it might affect your body. Your health is always the overriding consideration here so always seek your doctor’s advice before beginning any course of medication. Patients who are pregnant or breastfeeding should not take Glycomet. Additionally, alcohol should be avoided while taking it. These are some of the adverse side effects associated with the taking of Glycomet:

  • Breakout of skin rashes
  • Development of a bad taste in the mouth
  • Indicators of low blood sugar such as a rapid heartbeat, confusion, sweating, shaking, and irrational anger
  • Symptoms of gastrointestinal distress such as diarrhea (loose stools), vomiting, and nausea

Some conditions make the taking of Glycomet unwise for a patient. These conditions include:

  • A history of lactic acidosis
  • Kidney and liver diseases and conditions
  • Heart disorders such as congestive heart failure, myocardial infarction, or a past stroke
  • Type-1 diabetes


In patients taking somewhat high dosages of Glycomet (above 2000 mg per day), lactic acidosis (acid buildup in the bloodstream) might occur. This might escalate to present symptoms of an overdose which will include weakness, slowed heart rate, difficulty breathing, joint pains, and kidney problems. Should these symptoms present themselves and persist, emergency medical attention should be sought.

Interactions with other drugs

Interactions between drugs occur when a particular drug a patient might be taking has an effect on the activity of another drug the patient is simultaneously taking. This interference might neutralize, reduce, or increase the potency of one of the medications taken. In the case of Glycomet, these drugs will include:

  • Other diabetes medications including Repaglinide and Sulfonylureas
  • Corticosteroids including Cortisone and Prednisolone
  • Oral contraceptives such as Oestrogen
  • Anti-epileptic medications such as Phenytoin
  • High blood pressure and heart condition medications such as Nifedipine, beta-blockers, and diuretics
  • Diuretics such as Furosemide and Hydrochlorothiazide

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